Searchable abstracts of presentations at key conferences in endocrinology

ea0092ps3-24-04 | Thyroid Eye Disease | ETA2023

Rituximab treatment in patients with graves’ orbitopathy who are non-responsive to intravenous glucocorticoids is not better than IV glucocorticoids alone

Manousou Sofia , Holmberg Mats , Ekdahl Elin , Malmgren Helge , Skodell Lena , Filipsson Nystrom Helena

Background: Graves orbitopathy (GO) is the most frequent and feared complication of GravesÂ’ disease. In moderate-severe cases, intravenous (iv) glucocorticoids (GC) is the first-line treatment while Rituximab (RTX) is recommended as second-line treatment in patients non-responsive to GC. But data is scarce and contradictory.Objective: To investigate if patients with GO and poor response to iv GC benefit from a switch to RTX early in the treatment co...